Feb 1, 2022 · ... nsp15 protein) are crucial for hexamer formation [16]. From these, N164 (corresponding to N157 in MERS-CoV) is the only one found in SARS ...
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Jan 27, 2021 · The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor. J. Virol. 78 ...
The central portion of the MHV protein is more divergent than the comparable sequence from the SARS-CoV and IBV proteins. To help demonstrate the possible ...
Mar 10, 2021 · EndoU-deficient mutants presented defective viral protein synthesis in infected CEK cells. To analyze the mutational block in the IBV life cycle ...
May 8, 2017 · Because the N15m1 mutant virus is unique to this study, we investigated the effect of the T98M mutation on the nsp15 protein. The T98M ...
... (Nsp15) protein, a drug target known to play a crucial role in virulence of coronavirus. Method. Nsp15 protein was selected because it shows 89% similarity to ...
Apr 17, 2020 · The first two structures of Nsp15 were determined from mouse hepatitis virus (MHV; Protein ... The asymmetric unit contains two monomers of the ...
May 27, 2019 · Our findings highlight the importance of viral protein corona interactions for viral pathogenesis and provide a direct mechanistic link between ...
The term viral protein refers to both the products of the genome of a virus and any host proteins incorporated into the viral particle.
A viral protein can be a component as well as a product of the virus. Viral proteins include structural proteins as well as nonstructural (NS) proteins.